Fairbrother KJ, Heasman PA: Anticalculus agents. J Clin Periodontol ; the research associated with the development of anticalculus agents and to evalu-. Request PDF on ResearchGate | Anticalculus agents | Most dentifrices and some mouthrinses now contain 1 or more active anticalculus agents to achieve. With the help of antiplaque and anticalculus agents. Chemical plaque control – Rationale. Gingivitis & periodontitis are highly prevalent diseases and.
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After eight weeks, the person has significantly less calculus on his teeth than he did after the first eight weeks. Flavoring agents can also be added to the oral compositions of this invention to make them more palatable.
Preferred topical, oral carriers provide the desired characteristics for mouthwashes, mouth rinses, mouth sprays, dental treatment solutions, toothpastes, dental gels, toothpowders, prophylaxis pastes, and the like. JP Kind code of ref document: Oral composition exhibiting improved uptake and retention of antibacterial compounds on dental tissue surfaces. Request for preliminary examination filed after expiration of 19th month from priority date pct application filed from Wgents agent in certain embodiments comprises a zinc ion source.
Country of ref document: If present, the nutrients generally comprise from about 0. Preferably such compositions are held in the oral cavity for a period of time, and then largely expectorated rather than being swallowed.
At the end of the test the residual biofilm is dissolved in acid and tested for calcium content using inductively coupled plasma – optical emission spectroscopy ICP-OES which is conducted in a Good Clinical Practice GCP compliant laboratory. Additionally, tetrahydromagnolol and tetrahydrohonokiol are hydrogenated analogs of magnolol and honokiol often found in relatively small concentrations in the extracts of magnolia, and as such may be included in the antibacterial ingredient.
Antocalculus is also an anticalculus agent and, likewise, has an unpleasant taste which worsens with increased pyrophosphate concentration. But it has been developed and reformed till date only as a homecare adjunct to professional mechanical plaque control which still remains the gold standard to maintain a healthy periodontium and a healthy mouth. Instructions setting out such naticalculus schedule may be provided in commercial packaging with the product.
Following dental prophylaxis, a person brushes his teeth for sixty seconds twice daily antcalculus 1 g of a fluoride, non-anticalculus toothpaste.
For over 19 years our Clinical Research Services group has been a trusted partner for developers and manufacturers of oral care products. The agentw may be applied to the subject in any suitable manner known in the art such as, for example, by introducing the composition to the subjects oral cavity using a suitable applicator or delivery device such as a brush, dental strip, film, syringe, tape, pill or any other applicator or delivery device known in the art.
When the oral composition is a toothpaste, preferably from about 0. In one embodiment, 0. For this reason they are preferred for use herein. B01A Ref document number: After one week, the person has significantly less plaque on his teeth than he did after the first week. If added, anticalculud antibacterial active ingredients it is desirable that the additive does not substantially detract from the efficacy and bioavailability of the tartar control agents or the active compound of the extract.
In addition, all references cited herein are hereby incorporated by reference in their entireties. The silica abrasive can be precipitated silica or silica gels such as the silica xerogels described in U. Given the widespread presence of calculus, labour intensity, expense and discomfort of its mechanical removal there have been attempts at developing chemical approaches to calculus removal and inhibition.
During manufacture, the pH is maintained at a minimum of pH 7.
Bleaching agents can also be present in the oral compositions of this invention. Coloring agents may be added to compositions of this invention to improve appearance.
Auditing Consulting Sourcing Training. Colloidal magnesium aluminum silicate abticalculus finely divided silica can be used as part of the thickening agent to further improve texture. For example, while dentifrice containing no zinc salt Formulas 9 provided the delivery of The humectant serves to keep toothpaste compositions from hardening upon exposure to air, and to give mouthwash and toothpaste compositions a moist feel to the mouth.
Such an extraction may be carried out by conventional means known to one of skill in the art, for example, by using an extraction apparatus, such as a Soxhlet apparatus, which retains the solid material in a holder and allows the solvent to flow through the material; or by blending the solvent and material together and then separating the liquid and solid phases or two immiscible liquid phases, such as by filtration or by settling and decanting.
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