[ABSTRACT FROM AUTHOR]; Spanish: La nefrotoxicidad del cisplatino debe tenerse siempre presente como causa potencial de daño renal en todo fracaso. OBJECTIVE: To review recent advances in the understanding of the mechanisms of cisplatin nephrotoxicity. Factors affecting this toxicity and agents that may. Concluimos que la tiopronina, droga efectiva en la protección contra la nefrotoxicidad por cisplatino, es también efectiva para proteger en contra de la.
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The groups X axis are Control: Antihypertensive and vasodilator effects of methanolic and aqueous extracts of Tribulus terrestris in rats. The groups X axis are control: The obtained cissplatino weight, 6. Cypermethrin induced reproductive toxicity in male Wistar rats: Then, the tinctured grains were extracted by percolation method and extract concentrated in a vacuum and dried in the flat surface. Amifostine protective effect on cisplatin-treated rat testis.
These data supported other studies that indicated reductions in body weight could be attributable to toxic side effect of chemotherapeutic drugs and it suggests that T. The effect of toxic dose of cisplatin CIS 5. It is an efficient platinum-derived alkylating agent that acts in unspecific phases of the cellular cycle against proliferating and resting nefotoxicidad Lirdi et al.
In summary, we demonstrated that CP nephrotoxicity is the composite result of the transport of CP into renal epithelial cells, injury to nuclear and mitochondrial DNA and Finally Induction apoptosis.
Assessment of protective and anti-oxidant properties of Tribulus terrestris fruits hefrotoxicidad testicular toxicity in rats.
These parameters reached normal range after administration of nefrotoxiicidad extracts of TT for 4 days. Slides were mounted using glass cover slips and then analyzed immediately under a fluorescent microscope Olympus, Japan.
After dissolving the extract in distilled water, extract was immediately administered interaperitoneally to mice.
Thus, together with other herbal extracts, T. A combination of vitamin C and losartan for cisplatin-induced nephrotoxicity in rats.
The study demonstrates that extract of TT could have protective effect on cisplatin- induced apoptosis of kidney. Body weights of the mice were recorded initially and at the end of the experimental procedure day 5. Sections were dewaxed with xylene and rehydrated by standard methods and washed in deionized water.
Hoboken7: Differential roles of hydrogen peroxide and hydroxyl radical in cisplatin-induced cell death in renal proximal tubular epithelial cells.
Cisplatin; Nephrotoxicity; Tribulus terrestris; Kidneys; Protective effect. Experiments were started after one week of adaptation. Control group received saline, the first experimental group received cisplatin 5. Among its mechanisms of renal functional impairment are: Cellular and molecular studies on cisplatin-induced apoptotic cell death in rat kidney.
Tribulus terrestris L is also reported to have cooling, diuretic, tonic and aphrodisiac effects Sugunavarman et al. Tribulus terrestris extract protects against mercury-induced.
Evaluation of the aphrodisiac activity of Tribulus terrestris Linn. This abstract may be abridged. A single dose of CP caused apoptosis in kidney. Remote access cis;latino EBSCO’s databases is permitted to patrons of subscribing institutions accessing from remote locations for personal, non-commercial use.
Uno de los principales efectos secundarios limitantes del cisplatino es la nefrotoxicidad. Treatment of cisplatin-treated mice with T.
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